The Quraysh step up their hostilities
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The Quraysh treated the Messenger of Allah harshly ignoring the fact that he was a relative and deserved their respect.
One day while the Prophet was prostrating in the Masjid surrounded by some of the Quraysh, 'Uqbah ibn Abi Mu'ayt threw the innards of a slaughtered animal on the Prophet's back but he did not even lift his head. His daughter Fatimah came and removed them, cursing those who had committed the evil deed and the Prophet cursed them as well.
Another time, while the Prophet was praying in the Hijr of the Ka'bah, 'Uqbah ibn Abi Mu'ayt tried to throttle him with his own clothes. Abu Bakr grabbed 'Uqbah' shoulder and pulled him from the Prophet, saying, 'Would you kill a man just for saying, "My Lord is Allah"?'